Cancer of the Mesothelium Patients May Be Benefiting from Genetic Therapy Clinical Trials

Oncologists choose what type of treatment to prescribe for a patient. There are many options. There exists no universal treatment option for asbestos cancer sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.

The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) There are problems with all three. Traditional radiation therapy has not worked well with mesothelioma patients. Researches, concerned about damage to healthy tissue, are looking for ways to aim radiation directly at tumors.

Surgery takes out the mesothelial cancerous tissue around the tumor. The surgery is difficult and challenging, with unknown effects or benefits to patients. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different mixtures of these drugs have not been successful. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.

The high-mortality rate for mesothelioma patients means cutting-edge techniques for cancer are tried out. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.

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